Classification of anti-microbials ~ Perfect Medical Agency

Characterization of anti-microbials

Anti-infection agents: Antibiotics are the concoction remedial specialists of microbial or manufactured or semi-engineered inception which in bring down fixation repress the development of different microorganisms

Arrangement of anti-infection agents

A] based on compound structure

B] based on beginning

C] based on scope of movement ( range of action)

D] based on method of activity

E] based on impacts of their movement

F] based on course of organization

A] Classification of anti-toxins based on synthetic structure:

1. Starch containing Antibiotics:

2. Unadulterated saccharides anti-toxins: illustrations; Streptozotocin

3. Aminoglycosides: cases; Streptomycin

4. N/O glycosides: eg. Chromomycin

5. Other: eg; Lincomycin

6. Macrocyclic lactone anti-toxins: eg. Erythromycin

7. Quinolones anti-toxins; eg. Fluroquinolone

8. N-containing heterocyclic anti-toxins: eg. Beta-lactum

9. O-containing heterocyclic anti-toxins: eg. Cycloserine

10. Alicyclic anti-microbials: eg. Cycloheximide

11. Fragrant anti-microbials (Nitrobenzene): eg. Chloramphenicol

12. Aliphatic amine anti-microbials: eg. Spermidine

13.Peptide anti-microbials: eg. Polymyxin, Bacitracin, Gramicidin

B] Classification of anti-microbials based on cause:

1.Microbial cause:

I. Bacterial cause:

Bacillus polymyxa: Polymyxin

Chromobacter violaceum: Bacitracin

Micromonospora spp: Gentamycin

ii. Parasitic cause:

Penicillium notatum: Penicillin

Cephalosporin spp: Cephalosporin

iii. Actimomycetes cause:

Streptomyces griseus: Streptomycin

S. venezuelue: Chloramphenicol

S. erythreus: Erythromycin

S. mediterranae: Rifampicin

2. Semi-engineered anti-microbials:

Cases: Amoxycillin, Ampicillin, Doxycycline, Tigecycline, Sulfonamide and so on

3. Engineered anti-microbials:

Cases: Chloramphenicol, 4-quinolones, Sulfonamide

C] Classification of anti-microbials based on scope of action (range of action):

1.Narrow range:

Dynamic towards generally less microorganisms.

Cases: macrolides, Polymyxin

2. Direct range:

Dynamic towards Gram Positive microscopic organisms and in addition some fundamental and UTI causing Gram negative microbes.

Cases: Aminoglycosides, Sulfonamide

3. Thin Broad range:

Dynamic against Gram positive and gram negative

Cases: Beta-lactum

4. Wide range:

Dynamic against Gram positive and Gram negative with the exception of Pseudomonas and Mycobacteria.

Cases: Chloramphenicol, Tetracycline

5. Hostile to mycobacterial anti-infection agents:

Cases: Ethambutol, Rifampicin, Isoniazid, Pyrazinamide

D] Classification of anti-toxins based on Mode of activity:

1. Inhibitor of cell divider amalgamation/Peptidoglycan Inhibitors:

Cases:

Beta-lactum; Penicillin

Bacitracin

Cycloserine

Phosphomycin

Cephalosporin

Vancomycin

2. Inhibitor of protein amalgamation:

Cases:

Streptomycin

Aminoglycosides

Fusidic corrosive

Antibiotic medication

Mupirocin

Chloramphenicol

Macrolides

3. Inhibitor of Nucleic corrosive amalgamation:

Cases:

Quinolones

Ciprofloxacin

Nalidixic corrosive

Metronidazole

Nitrofurantoin

4. Inhibitor of folic corrosive amalgamation (Folate hostile)

Cases:

Sulfonamide

Trimethoprim

5. Inhibitor of cytoplasmic layer:

Cases:

Polymyxin; Colistin

E] Classification of anti-toxins based on impacts of their movement:

1. Bactericidal:

Eliminates microscopic organisms

Cases: Aminoglycosides, Penicillin, Cephalosporin

2. Bacteriostatic:

Represses the development of microorganisms

Cases: Sulfonamide, antibiotic medication, chloramphenicol, trimethoprim, macrolides, Lincosamide

F] Classification of anti-toxins based on Route of organization:

1. Oral anti-toxins:

Corrosive stable anti-toxins,

Illustrations; Penicillin V

2. Parenteral course:

Intravenous organization

Illustrations; Penicillin G

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